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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIAA1688 All Species: 14.55
Human Site: S139 Identified Species: 40
UniProt: Q9C0H5 Number Species: 8
    Phosphosite Substitution
    Charge Score: -0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9C0H5 NP_079527.1 1083 121286 S139 R E G S T S S S L E P E P D T
Chimpanzee Pan troglodytes XP_520025 1126 126113 S139 R E G S T S S S L E P E P D T
Rhesus Macaque Macaca mulatta XP_001095036 1083 121236 S139 R E G S T S S S L E P E P D T
Dog Lupus familis XP_539224 1015 113288 H136 T T Q R T V W H R P Q D C D I
Cat Felis silvestris
Mouse Mus musculus P59281 1107 125188 S136 R D G S T G S S L E P E L E E
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_417317 1381 150829 P418 Q Q T V W H R P Q G C D I V P
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001007296 1067 119680 K135 K E P E C A S K E P K E P E M
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_392788 1054 119503 S135 E S I K N Q K S V P L G E P P
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_798334 1348 153268 S189 H Q G V M H G S P R G Q R S Q
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 94.7 98.9 75.2 N.A. 86.9 N.A. N.A. N.A. 33.9 N.A. 42.1 N.A. N.A. 27.5 N.A. 26.7
Protein Similarity: 100 95.1 99.6 79.4 N.A. 90.8 N.A. N.A. N.A. 46.9 N.A. 56.1 N.A. N.A. 43.7 N.A. 40.1
P-Site Identity: 100 100 100 13.3 N.A. 66.6 N.A. N.A. N.A. 0 N.A. 26.6 N.A. N.A. 6.6 N.A. 13.3
P-Site Similarity: 100 100 100 20 N.A. 80 N.A. N.A. N.A. 20 N.A. 46.6 N.A. N.A. 13.3 N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 12 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 12 0 0 0 0 0 12 0 12 0 0 % C
% Asp: 0 12 0 0 0 0 0 0 0 0 0 23 0 45 0 % D
% Glu: 12 45 0 12 0 0 0 0 12 45 0 56 12 23 12 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 56 0 0 12 12 0 0 12 12 12 0 0 0 % G
% His: 12 0 0 0 0 23 0 12 0 0 0 0 0 0 0 % H
% Ile: 0 0 12 0 0 0 0 0 0 0 0 0 12 0 12 % I
% Lys: 12 0 0 12 0 0 12 12 0 0 12 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 45 0 12 0 12 0 0 % L
% Met: 0 0 0 0 12 0 0 0 0 0 0 0 0 0 12 % M
% Asn: 0 0 0 0 12 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 12 0 0 0 0 12 12 34 45 0 45 12 23 % P
% Gln: 12 23 12 0 0 12 0 0 12 0 12 12 0 0 12 % Q
% Arg: 45 0 0 12 0 0 12 0 12 12 0 0 12 0 0 % R
% Ser: 0 12 0 45 0 34 56 67 0 0 0 0 0 12 0 % S
% Thr: 12 12 12 0 56 0 0 0 0 0 0 0 0 0 34 % T
% Val: 0 0 0 23 0 12 0 0 12 0 0 0 0 12 0 % V
% Trp: 0 0 0 0 12 0 12 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _